Lines of research
Computational analysis of biological macromolecules and systems: protein structure, function, evolution and design; protein and nucleic acid dynamics and interactions. Genomics and genome data analysis. Drug Design. Software and algorithms for bioinformatics.
Protein folding and protein recognition, protein stability, protein-protein, protein nucleic acid and protein-ligand interactions, enzymatic catalysis,redox catalysis and bioenergetics.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
Metabolic engineering,neurodegenerative and infectious diseases, drug delivery and nanotechnology, drug targets in cancer and parasites, bioactive compounds and peptides, enzymatic synthesis in green chemistry
X-ray crystallography, single particle cryo-EM, characterization of protein-protein, protein nucleic acid and protein-ligand complexes.
BIOCHEMISTRY OF CELLULAR PROCESSES
Patho-physiological processes in cells, drug targets in cancer, neurodegeneration and other chronic and degenerative diseases, oxidative stress, cancer metabolism, energy metabolism, metabolism of vitamins, metals and cofactors, signal transduction, cellular processes in pathogenic microorganisms.
CELLULAR PROTEOMICS AND METABOLOMICS
Redox proteomics, cancer metabolism, protein modification in cell signal transduction, cancer, neurodegeneration and other chronic and degenerative diseases, transcriptomics.